The Allergy and Asthma Foundation of America has ranked cities on how difficult it is to live there based on allergies.
The worst place for folks with allergies is Scranton PA. Columbia SC ranks as the 14th worst. Greenville SC is #25. Charleston is #31.
Based on Spring Allergies Columbia jumps up to 12th and in the Fall we drop to 16th.
You can see the entire report here.